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Idiotype connectance in the immune system. II. A heavy chain variable region idiotope that dominates the antibody response to the p- azobenzenearsonate group is a minor idiotope in the response to trinitrophenyl group
We describe the recurrence of a cross-reactive idiotope (CRIAD8) in antibody responses to different epitopes, and explore factors leading to its dominance in some responses, but not others. Serological and genomic DNA analyses showed that CRIAD8 is a marker of the CRIa heavy chain variable region (V...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1985
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187547/ https://www.ncbi.nlm.nih.gov/pubmed/2578546 |