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Eleven distinct VH gene families and additional patterns of sequence variation suggest a high degree of immunoglobulin gene complexity in a lower vertebrate, Xenopus laevis
Lower vertebrate species, including Xenopus laevis, exhibit restricted antibody diversity relative to higher vertebrates. We have analyzed more than 180 VH gene-containing recombinant clones from an unamplified spleen cDNA library by selective sequencing of JH and CH positive clones following iterat...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187900/ https://www.ncbi.nlm.nih.gov/pubmed/2110243 |