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Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors

Tumor necrosis factor (TNF) is a monocyte-derived protein cytotoxic or cytostatic for some tumor cell lines. Here we show that highly purified E. coli-derived recombinant human TNF stimulated the growth of human FS- 4 diploid fibroblasts. Stimulation of cell growth was demonstrable at a TNF concentr...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1986
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188056/
https://www.ncbi.nlm.nih.gov/pubmed/3512757