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Pancreatic islet cell surface glycoproteins containing Gal beta 1- 4GlcNAc-R identified by a cytotoxic monoclonal autoantibody

To investigate the autoimmune pathogenesis of spontaneously occurring diabetes mellitus in BB rats, spleen cells of newly diagnosed diabetic BB rats were fused with mouse myeloma cells. Hybridoma supernatants were screened for antibodies by indirect immunofluorescence and by 51Cr- release assays usi...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188266/
https://www.ncbi.nlm.nih.gov/pubmed/2432147