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Pancreatic islet cell surface glycoproteins containing Gal beta 1- 4GlcNAc-R identified by a cytotoxic monoclonal autoantibody
To investigate the autoimmune pathogenesis of spontaneously occurring diabetes mellitus in BB rats, spleen cells of newly diagnosed diabetic BB rats were fused with mouse myeloma cells. Hybridoma supernatants were screened for antibodies by indirect immunofluorescence and by 51Cr- release assays usi...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1987
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188266/ https://www.ncbi.nlm.nih.gov/pubmed/2432147 |
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