Dissociation of membrane binding and lytic activities of the lymphocyte pore-forming protein (perforin)

Granules isolated from CTL and NK cells contain a cytolytic pore- forming protein (PFP/perforin). At low temperatures (on ice), PFP binds to erythrocyte membranes without producing hemolysis. Hemolysis occurs when the PFP-bound erythrocytes are warmed up to 37 degrees C, which defines a temperature-...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1987
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188309/
https://www.ncbi.nlm.nih.gov/pubmed/3494808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188309/
https://www.ncbi.nlm.nih.gov/pubmed/3494808

Ejemplares similares