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Heavy-chain class switch does not terminate somatic mutation
We studied the H-chain class switch rearrangement in four groups of clonally related B cell hybridomas, to test the hypothesis that class switch terminates somatic mutation in a B cell. Using switch region- specific probes in Southern blot analysis individual mu-gamma switch rearrangement events can...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188341/ https://www.ncbi.nlm.nih.gov/pubmed/2115570 |