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Identification of an immunodominant region on the I-A beta chain using site-directed mutagenesis and DNA-mediated gene transfer
To identify which polymorphic residues determine the allospecific antibody binding sites on A beta polypeptides, mutant Ak beta genes were constructed encoding single or multiple amino acids of the d allele at 14 polymorphic positions in the beta 1 domain. Cell lines expressing these genes were anal...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1988
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188829/ https://www.ncbi.nlm.nih.gov/pubmed/2450160 |