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Point mutations cause the somatic diversification of IgM and IgG2a antiphosphorylcholine antibodies [published erratum appears in J Exp Med 1990 Aug 1;172(2):669]
The genetic mechanism responsible for the somatic diversification of two mAbs was determined. The two PC-binding hybridomas were representative of events early and late in the immune response. The P28 cell line that produces an IgM antibody and thus represents events early in the immune response, wa...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1988
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188873/ https://www.ncbi.nlm.nih.gov/pubmed/3127529 |