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Plasminogen activator inhibitor 1 and 2 are tumor necrosis factor/cachectin-responsive genes
Human rTNF/Cachectin was shown to stimulate gene transcription of plasminogen activator inhibitor (PA1)-1 and PAI-2, and simultaneously suppress constitutive gene expression of tissue-type plasminogen activator (t-PA) in human fibrosarcoma cells. We propose that a TNF- mediated reprogramming of gene...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1988
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188989/ https://www.ncbi.nlm.nih.gov/pubmed/3137305 |