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Dissection of the human CD2 intracellular domain. Identification of a segment required for signal transduction and interleukin 2 production

To evaluate those residues in the 117 amino acids of the CD2 cytoplasmic domain required for transduction of T lymphocyte activation signals, a full-length human CD2 cDNA and a series of deletion and substitution mutants were inserted into the ovalbumin-specific, I-Ad- restricted murine T cell hybri...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189358/
https://www.ncbi.nlm.nih.gov/pubmed/2567337