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Dissection of the human CD2 intracellular domain. Identification of a segment required for signal transduction and interleukin 2 production
To evaluate those residues in the 117 amino acids of the CD2 cytoplasmic domain required for transduction of T lymphocyte activation signals, a full-length human CD2 cDNA and a series of deletion and substitution mutants were inserted into the ovalbumin-specific, I-Ad- restricted murine T cell hybri...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1989
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189358/ https://www.ncbi.nlm.nih.gov/pubmed/2567337 |