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Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells

To study the nature of tolerance to antigens not expressed by cells of the lymphoid system, expression of class II MHC I-E was targeted to the acinar cells of the exocrine pancreas in transgenic mice (elastase [EL]- I-E). Despite the absence of detectable I-E in the thymus of EL-I-E transgenic mice,...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189391/
https://www.ncbi.nlm.nih.gov/pubmed/2526197