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In individual T cells one productive alpha rearrangement does not appear to block rearrangement at the second allele [retracted by Hood L, Urban JL. In: J Exp Med 1990 Sep 1;172(3):1005]
The T cell lymphoma line BW5147 has rearranged TCR alpha chain genes segments on both the homologous chromosomes: one is functional (V alpha 1) and the second (V alpha 16.1) is a pseudogene. The extreme 3' position of the V alpha 16.1 gene segment in the V alpha locus allows us to recognize rea...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1989
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189552/ https://www.ncbi.nlm.nih.gov/pubmed/2555431 |