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Negative Regulation of the Sapk/Jnk Signaling Pathway by Presenilin 1

Presenilin 1 (PS1) plays a pivotal role in Notch signaling and the intracellular metabolism of the amyloid β-protein. To understand intracellular signaling events downstream of PS1, we investigated in this study the action of PS1 on mitogen-activated protein kinase pathways. Overexpressed PS1 suppre...

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Detalles Bibliográficos
Autores principales: Kim, Jin Woo, Chang, Tong-Shin, Lee, Ji Eun, Huh, Sung-Ho, Yeon, Seung Woo, Yang, Wan Seok, Joe, Cheol O., Mook-Jung, Inhee, Tanzi, Rudolph E., Kim, Tae-Wan, Choi, Eui-Ju
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190568/
https://www.ncbi.nlm.nih.gov/pubmed/11331298