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Negative Regulation of the Sapk/Jnk Signaling Pathway by Presenilin 1
Presenilin 1 (PS1) plays a pivotal role in Notch signaling and the intracellular metabolism of the amyloid β-protein. To understand intracellular signaling events downstream of PS1, we investigated in this study the action of PS1 on mitogen-activated protein kinase pathways. Overexpressed PS1 suppre...
Autores principales: | Kim, Jin Woo, Chang, Tong-Shin, Lee, Ji Eun, Huh, Sung-Ho, Yeon, Seung Woo, Yang, Wan Seok, Joe, Cheol O., Mook-Jung, Inhee, Tanzi, Rudolph E., Kim, Tae-Wan, Choi, Eui-Ju |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190568/ https://www.ncbi.nlm.nih.gov/pubmed/11331298 |
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