Merotelic Kinetochore Orientation Is a Major Mechanism of Aneuploidy in Mitotic Mammalian Tissue Cells

In mitotic cells, an error in chromosome segregation occurs when a chromosome is left near the spindle equator after anaphase onset (lagging chromosome). In PtK1 cells, we found 1.16% of untreated anaphase cells exhibiting lagging chromosomes at the spindle equator, and this percentage was enhanced...

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Detalles Bibliográficos
Autores principales: Cimini, Daniela, Howell, Bonnie, Maddox, Paul, Khodjakov, Alexey, Degrassi, Francesca, Salmon, E.D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190575/
https://www.ncbi.nlm.nih.gov/pubmed/11331303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190575/
https://www.ncbi.nlm.nih.gov/pubmed/11331303

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