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An Rgd Sequence in the P2y(2) Receptor Interacts with α(V)β(3) Integrins and Is Required for G(o)-Mediated Signal Transduction
The P2Y(2) nucleotide receptor (P2Y(2)R) contains the integrin-binding domain arginine-glycine-aspartic acid (RGD) in its first extracellular loop, raising the possibility that this G protein–coupled receptor interacts directly with an integrin. Binding of a peptide corresponding to the first extrac...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190579/ https://www.ncbi.nlm.nih.gov/pubmed/11331301 |