Necrotic Death Pathway in FAS Receptor Signaling

A caspase 8–deficient subline (JB6) of human Jurkat cells can be killed by the oligomerization of Fas-associated protein with death domain (FADD). This cell death process is not accompanied by caspase activation, but by necrotic morphological changes. Here, we show that the death effector domain of...

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Detalles Bibliográficos
Autores principales: Matsumura, Hirotaka, Shimizu, Yusuke, Ohsawa, Yoshiyuki, Kawahara, Atsuo, Uchiyama, Yasuo, Nagata, Shigekazu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190580/
https://www.ncbi.nlm.nih.gov/pubmed/11121439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190580/
https://www.ncbi.nlm.nih.gov/pubmed/11121439

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