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The origins and early evolution of DNA mismatch repair genes—multiple horizontal gene transfers and co-evolution

To understand the evolutionary process of the DNA mismatch repair system, we conducted systematic phylogenetic analysis of its key components, the bacterial MutS and MutL genes and their eukaryotic homologs. Based on genome-wide homolog searches, we identified three new MutS subfamilies (MutS3-5) in...

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Detalles Bibliográficos
Autores principales: Lin, Zhenguo, Nei, Masatoshi, Ma, Hong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190696/
https://www.ncbi.nlm.nih.gov/pubmed/17965091
http://dx.doi.org/10.1093/nar/gkm921