Contributions of DNA interstrand cross-links to aging of cells and organisms

Impaired DNA damage repair, especially deficient transcription-coupled nucleotide excision repair, leads to segmental progeroid syndromes in human patients as well as in rodent models. Furthermore, DNA double-strand break signalling has been pinpointed as a key inducer of cellular senescence. Severa...

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Detalles Bibliográficos
Autores principales: Grillari, Johannes, Katinger, Hermann, Voglauer, Regina
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190700/
https://www.ncbi.nlm.nih.gov/pubmed/18083760
http://dx.doi.org/10.1093/nar/gkm1065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190700/
https://www.ncbi.nlm.nih.gov/pubmed/18083760
http://dx.doi.org/10.1093/nar/gkm1065

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