Lentivirus-mediated antagomir expression for specific inhibition of miRNA function

Micro RNAs (miRNA) regulate gene expression by hybridization and recruitment of multi-protein complexes to complementary mRNA target sequences. miRNA function can transiently be antagonized by antagomirs—chemically modified oligonucleotides complementary to individual miRNAs. Here, we describe the i...

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Detalles Bibliográficos
Autores principales: Scherr, Michaela, Venturini, Letizia, Battmer, Karin, Schaller-Schoenitz, Michael, Schaefer, Daniel, Dallmann, Iris, Ganser, Arnold, Eder, Matthias
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190705/
https://www.ncbi.nlm.nih.gov/pubmed/18025036
http://dx.doi.org/10.1093/nar/gkm971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190705/
https://www.ncbi.nlm.nih.gov/pubmed/18025036
http://dx.doi.org/10.1093/nar/gkm971

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