Cargando…

Lentivirus-mediated antagomir expression for specific inhibition of miRNA function

Micro RNAs (miRNA) regulate gene expression by hybridization and recruitment of multi-protein complexes to complementary mRNA target sequences. miRNA function can transiently be antagonized by antagomirs—chemically modified oligonucleotides complementary to individual miRNAs. Here, we describe the i...

Descripción completa

Detalles Bibliográficos
Autores principales: Scherr, Michaela, Venturini, Letizia, Battmer, Karin, Schaller-Schoenitz, Michael, Schaefer, Daniel, Dallmann, Iris, Ganser, Arnold, Eder, Matthias
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190705/
https://www.ncbi.nlm.nih.gov/pubmed/18025036
http://dx.doi.org/10.1093/nar/gkm971

Ejemplares similares