Exploring the sequence space of a DNA aptamer using microarrays

The relationship between sequence and binding properties of an aptamer for immunoglobulin E (IgE) was investigated using custom DNA microarrays. Single, double and some triple mutations of the aptamer sequence were created to evaluate the importance of specific base composition on aptamer binding. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Katilius, Evaldas, Flores, Carole, Woodbury, Neal W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190713/
https://www.ncbi.nlm.nih.gov/pubmed/17981839
http://dx.doi.org/10.1093/nar/gkm922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190713/
https://www.ncbi.nlm.nih.gov/pubmed/17981839
http://dx.doi.org/10.1093/nar/gkm922

Ejemplares similares