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DNA damage, cellular senescence and organismal ageing: causal or correlative?
Cellular senescence has long been used as a cellular model for understanding mechanisms underlying the ageing process. Compelling evidence obtained in recent years demonstrate that DNA damage is a common mediator for both replicative senescence, which is triggered by telomere shortening, and prematu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190714/ https://www.ncbi.nlm.nih.gov/pubmed/17913751 http://dx.doi.org/10.1093/nar/gkm681 |