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Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

Guanine-rich DNA sequences can form G-quadruplexes stabilized by stacked G–G–G–G tetrads in monovalent cation-containing solution. The length and number of individual G-tracts and the length and sequence context of linker residues define the diverse topologies adopted by G-quadruplexes. The review h...

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Detalles Bibliográficos
Autores principales: Patel, Dinshaw J., Phan, Anh Tuân, Kuryavyi, Vitaly
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190718/
https://www.ncbi.nlm.nih.gov/pubmed/17913750
http://dx.doi.org/10.1093/nar/gkm711