Cargando…

Two faces of p53: aging and tumor suppression

The p53 tumor suppressor protein, often termed guardian of the genome, integrates diverse physiological signals in mammalian cells. In response to stress signals, perhaps the best studied of which is the response to DNA damage, p53 becomes functionally active and triggers either a transient cell cyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodier, Francis, Campisi, Judith, Bhaumik, Dipa
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190721/
https://www.ncbi.nlm.nih.gov/pubmed/17942417
http://dx.doi.org/10.1093/nar/gkm744