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Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex
Transgenic murine lines have been constructed that express a chimeric class I molecule composed of the alpha 1 and alpha 2 domains of HLA- A2.1 and the alpha 3, transmembrane, and cytoplasmic domains of H-2Kb. Upon immunization with influenza virus, transgenic mice developed a strong A2.1Kb-restrict...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1991
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190816/ https://www.ncbi.nlm.nih.gov/pubmed/1706750 |