Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

The nef gene product encoded by the mac239 proviral clone of simian immunodeficiency virus (SIV) markedly enhances viral replication and pathogenesis in vivo. We have used this biologically active nef isolate to examine the phenotype of Nef in retrovirally transduced human T cells in culture. SIV Ne...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1993
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191034/
https://www.ncbi.nlm.nih.gov/pubmed/8098729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191034/
https://www.ncbi.nlm.nih.gov/pubmed/8098729

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