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CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production
Naive T cells require interleukin 4 (IL-4) to develop into IL-4- producing T cells and IL-4 blocks development of such cells into interferon gamma (IFN-gamma) producers. Prior studies in accessory cell- independent priming systems using antireceptor antibodies as agonists have demonstrated that IL-2...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191346/ https://www.ncbi.nlm.nih.gov/pubmed/8270872 |