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The combination of anti-B7 monoclonal antibody and cyclosporin A induces alloantigen-specific anergy during a primary mixed lymphocyte reaction
Interaction of CD28/CTLA-4 on T cells with B7 on antigen-presenting cells constitutes an important costimulatory signal for T cells and is responsible for cyclosporin A-resistant interleukin 2 (IL-2) gene expression and potentially also for prevention of anergy induction after T cell receptor trigge...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1994
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191375/ https://www.ncbi.nlm.nih.gov/pubmed/7507511 |