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Leukocyte common antigen (CD45) is required for immunoglobulin E- mediated degranulation of mast cells
We demonstrate using primary mast cell cultures derived from wild-type and CD45-deficient mice that mast cell triggering through the high- affinity immunoglobulin E (IgE) receptor requires the cell surface tyrosine phosphatase CD45. Unlike wild-type cells, cross-linking of surface-bound IgE in mast...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191589/ https://www.ncbi.nlm.nih.gov/pubmed/8046327 |