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Humoral immune responses in CD40 ligand-deficient mice
Individuals with X-linked hyper-IgM syndrome fail to express functional CD40 ligand (CD40L) and, as a consequence, are incapable of mounting protective antibody responses to opportunistic bacterial infections. To address the role of CD40L in humoral immunity, we created, through homologous recombina...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191723/ https://www.ncbi.nlm.nih.gov/pubmed/7964465 |