Metaphase Arrest with Centromere Separation in polo Mutants of Drosophila

The Drosophila gene polo encodes a conserved protein kinase known to be required to organize spindle poles and for cytokinesis. Here we report two strongly hypomorphic mutations of polo that arrest cells of the larval brain at a point in metaphase when the majority of sister kinetochores have separa...

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Detalles Bibliográficos
Autores principales: Donaldson, Mary M., Tavares, Álvaro A.M., Ohkura, Hiroyuki, Deak, Peter, Glover, David M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192380/
https://www.ncbi.nlm.nih.gov/pubmed/11352929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192380/
https://www.ncbi.nlm.nih.gov/pubmed/11352929

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