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Metaphase Arrest with Centromere Separation in polo Mutants of Drosophila
The Drosophila gene polo encodes a conserved protein kinase known to be required to organize spindle poles and for cytokinesis. Here we report two strongly hypomorphic mutations of polo that arrest cells of the larval brain at a point in metaphase when the majority of sister kinetochores have separa...
Autores principales: | Donaldson, Mary M., Tavares, Álvaro A.M., Ohkura, Hiroyuki, Deak, Peter, Glover, David M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192380/ https://www.ncbi.nlm.nih.gov/pubmed/11352929 |
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