Role of Phosphatidylinositol 3′ Kinase and a Downstream Pleckstrin Homology Domain–Containing Protein in Controlling Chemotaxis inDictyostelium

We show that cells lacking two Dictyostelium class I phosphatidylinositol (PI) 3′ kinases (PI3K and pi3k1/2-null cells) or wild-type cells treated with the PI3K inhibitor LY294002 are unable to properly polarize, are very defective in the temporal, spatial, and quantitative regulation of chemoattrac...

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Detalles Bibliográficos
Autores principales: Funamoto, Satoru, Milan, Kristina, Meili, Ruedi, Firtel, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192389/
https://www.ncbi.nlm.nih.gov/pubmed/11352940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192389/
https://www.ncbi.nlm.nih.gov/pubmed/11352940

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