Biogenesis of the Signal Recognition Particle (Srp) Involves Import of Srp Proteins into the Nucleolus, Assembly with the Srp-Rna, and Xpo1p-Mediated Export

The signal recognition particle (SRP) targets nascent secretory proteins to the ER, but how and where the SRP assembles is largely unknown. Here we analyze the biogenesis of yeast SRP, which consists of an RNA molecule (scR1) and six proteins, by localizing all its components. Although scR1 is cytop...

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Detalles Bibliográficos
Autores principales: Grosshans, Helge, Deinert, Karina, Hurt, Ed, Simos, George
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192394/
https://www.ncbi.nlm.nih.gov/pubmed/11352936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192394/
https://www.ncbi.nlm.nih.gov/pubmed/11352936

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