Cargando…
Biogenesis of the Signal Recognition Particle (Srp) Involves Import of Srp Proteins into the Nucleolus, Assembly with the Srp-Rna, and Xpo1p-Mediated Export
The signal recognition particle (SRP) targets nascent secretory proteins to the ER, but how and where the SRP assembles is largely unknown. Here we analyze the biogenesis of yeast SRP, which consists of an RNA molecule (scR1) and six proteins, by localizing all its components. Although scR1 is cytop...
Autores principales: | Grosshans, Helge, Deinert, Karina, Hurt, Ed, Simos, George |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192394/ https://www.ncbi.nlm.nih.gov/pubmed/11352936 |
Ejemplares similares
-
Isolating SRP
por: Leslie, Mitch
Publicado: (2005) -
Structure and function of the signal recognition particle (SRP)
por: Dobberstein, Bernhard
Publicado: (1987) -
Myristoylation versus SRP
por: LeBrasseur, Nicole
Publicado: (2005) -
Structures of SRP54 and SRP19, the Two Proteins that Organize the Ribonucleic Core of the Signal Recognition Particle from Pyrococcus furiosus
por: Egea, Pascal F., et al.
Publicado: (2008) -
Exportin-5 mediates nuclear export of SRP RNA in vertebrates
por: Takeiwa, Toshihiko, et al.
Publicado: (2015)