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Ig-specific T cell receptor-transgenic T cells are not deleted in the thymus and are functional in vivo
The mechanisms that induce T cell tolerance to circulating self- proteins are still controversial, and both the deletion and selection of autoreactive T cells have been observed in the thymus of transgenic mouse models. To address the question of the induction of tolerance to circulating self-consti...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1996
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192416/ https://www.ncbi.nlm.nih.gov/pubmed/8551224 |