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Ig-specific T cell receptor-transgenic T cells are not deleted in the thymus and are functional in vivo

The mechanisms that induce T cell tolerance to circulating self- proteins are still controversial, and both the deletion and selection of autoreactive T cells have been observed in the thymus of transgenic mouse models. To address the question of the induction of tolerance to circulating self-consti...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192416/
https://www.ncbi.nlm.nih.gov/pubmed/8551224