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The immunosuppressant 15-deoxyspergualin [correction of 1,5- deoxyspergualin] reveals commonality between preT and preB cell differentiation

15 [correction of 1,5] deoxyspergualin (DSG) is a potent immunosuppressant whose mechanism of action is still somewhat of a mystery. We have studied the generation of lymphocytes in mice treated with this drug. The differentiation of T cells in the thymus was blocked at an important early control po...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192603/
https://www.ncbi.nlm.nih.gov/pubmed/8676063