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Decreased C-Src Expression Enhances Osteoblast Differentiation and Bone Formation

c-src deletion in mice leads to osteopetrosis as a result of reduced bone resorption due to an alteration of the osteoclast. We report that deletion/reduction of Src expression enhances osteoblast differentiation and bone formation, contributing to the increase in bone mass. Bone histomorphometry sh...

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Detalles Bibliográficos
Autores principales: Marzia, Marilena, Sims, Natalie A., Voit, Susanne, Migliaccio, Silvia, Taranta, Anna, Bernardini, Silvia, Faraggiana, Tullio, Yoneda, Toshiyuki, Mundy, Gregory R., Boyce, Brendan F., Baron, Roland, Teti, Anna
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192638/
https://www.ncbi.nlm.nih.gov/pubmed/11038178