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Ectodomain Shedding of Epidermal Growth Factor Receptor Ligands Is Required for Keratinocyte Migration in Cutaneous Wound Healing

Keratinocyte proliferation and migration are essential to cutaneous wound healing and are, in part, mediated in an autocrine fashion by epidermal growth factor receptor (EGFR)–ligand interactions. EGFR ligands are initially synthesized as membrane-anchored forms, but can be processed and shed as sol...

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Detalles Bibliográficos
Autores principales: Tokumaru, Sho, Higashiyama, Shigeki, Endo, Takeshi, Nakagawa, Takatoshi, Miyagawa, Jun-ichiro, Yamamori, Katsumi, Hanakawa, Yasushi, Ohmoto, Hiroshi, Yoshino, Kohichiro, Shirakata, Yuji, Matsuzawa, Yuji, Hashimoto, Koji, Taniguchi, Naoyuki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192647/
https://www.ncbi.nlm.nih.gov/pubmed/11038170