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Role of the Pi3k Regulatory Subunit in the Control of Actin Organization and Cell Migration

Cell migration represents an important cellular response that utilizes cytoskeletal reorganization as its driving force. Here, we describe a new signaling cascade linking PDGF receptor stimulation to actin rearrangements and cell migration. We demonstrate that PDGF activates Cdc42 and its downstream...

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Detalles Bibliográficos
Autores principales: Jiménez, Concepción, Portela, Rosario Armas, Mellado, Mario, Rodríguez-Frade, Jose Miguel, Collard, John, Serrano, Antonio, Martínez-A, Carlos, Avila, Jesus, Carrera, Ana C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192656/
https://www.ncbi.nlm.nih.gov/pubmed/11038173