Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion

Many viral fusion proteins exhibit a six-helix bundle as a core structure. HIV Env–induced fusion was studied to resolve whether membrane merger was due to the transition into the bundle configuration or occurred after bundle formation. Suboptimal temperature was used to arrest fusion at an intermed...

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Detalles Bibliográficos
Autores principales: Melikyan, Grigory B., Markosyan, Ruben M., Hemmati, Hila, Delmedico, Mary K., Lambert, Dennis M., Cohen, Fredric S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192659/
https://www.ncbi.nlm.nih.gov/pubmed/11038187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192659/
https://www.ncbi.nlm.nih.gov/pubmed/11038187

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