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Limited role of CD28-mediated signals in T helper subset differentiation
The role of CD28-mediated signals in T helper cell maturation is not fully understood. We tested the requirement for costimulation through CD28 in several systems of CD4+, T cell differentiation. In vivo priming of mice with genetic disruption of CD28 (CD28-/-) yielded normal levels of antigen-speci...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1996
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192778/ https://www.ncbi.nlm.nih.gov/pubmed/9064340 |