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Gene vaccination with naked plasmid DNA: mechanism of CTL priming
The injection of naked plasmid DNA directly into the muscle cells of mice has been shown to induce potent humoral and cellular immune responses. The generation of a cytotoxic T lymphocyte (CTL) response after plasmid DNA injection may involve the presentation of the expressed antigen in the context...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1996
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192808/ https://www.ncbi.nlm.nih.gov/pubmed/8879229 |