Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLIP)

Invariant chain (Ii) associates with newly synthesized class II molecules in the endoplasmic reticulum (ER), an interaction that has been shown to interfere with peptide binding to class II molecules. The class II-associated invariant chain peptide (CLIP) region (residues 81- 104) of Ii is believed...

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Detalles Bibliográficos

Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1996
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192887/ https://www.ncbi.nlm.nih.gov/pubmed/8920896