Molecular Requirements for T Cell Recognition by a Major Histocompatibility Complex Class II–restricted T Cell Receptor: The Involvement of the Fourth Hypervariable Loop of the Vα Domain

The role of two central residues (K68, E69) of the fourth hypervariable loop of the Vα domain (HV4α) in antigen recognition by an MHC class II–restricted T cell receptor (TCR) has been analyzed. The TCR recognizes the NH(2)-terminal peptide of myelin basic protein (Ac1-11, acetylated at NH(2) termin...

Descripción completa

Detalles Bibliográficos
Autores principales: Thatte, Jayant, Qadri, Ayub, Radu, Caius, Ward, E. Sally
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192911/
https://www.ncbi.nlm.nih.gov/pubmed/9927513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192911/
https://www.ncbi.nlm.nih.gov/pubmed/9927513

Ejemplares similares