Cargando…
Molecular Requirements for T Cell Recognition by a Major Histocompatibility Complex Class II–restricted T Cell Receptor: The Involvement of the Fourth Hypervariable Loop of the Vα Domain
The role of two central residues (K68, E69) of the fourth hypervariable loop of the Vα domain (HV4α) in antigen recognition by an MHC class II–restricted T cell receptor (TCR) has been analyzed. The TCR recognizes the NH(2)-terminal peptide of myelin basic protein (Ac1-11, acetylated at NH(2) termin...
Autores principales: | Thatte, Jayant, Qadri, Ayub, Radu, Caius, Ward, E. Sally |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192911/ https://www.ncbi.nlm.nih.gov/pubmed/9927513 |
Ejemplares similares
-
Genetic basis for T cell recognition of a major histocompatibility complex class II-restricted neo-self peptide
Publicado: (1995) -
Recognition of carbohydrate by major histocompatibility complex class I- restricted, glycopeptide-specific cytotoxic T lymphocytes
Publicado: (1994) -
Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis
por: Santamaria, Salvatore, et al.
Publicado: (2019) -
Recognition of major histocompatibility complex class I antigens by natural killer cells
Publicado: (1994) -
Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity
Publicado: (1996)