Severe Attenuation of the B Cell Immune Response in Msh2-deficient Mice

Recently, results obtained from mice with targeted inactivations of postreplication DNA mismatch repair (MMR) genes have been interpreted to demonstrate a direct role for MMR in antibody variable (V) gene hypermutation. Here we show that mice that do not express the MMR factor Msh2 have wide-ranging...

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Detalles Bibliográficos
Autores principales: Vora, Kalpit A., Tumas-Brundage, Kathleen M., Lentz, Vicky M., Cranston, Aaron, Fishel, Richard, Manser, Tim
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192912/
https://www.ncbi.nlm.nih.gov/pubmed/9927509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192912/
https://www.ncbi.nlm.nih.gov/pubmed/9927509

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