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Antigen-pulsed CD8α(+) Dendritic Cells Generate an Immune Response after Subcutaneous Injection without Homing to the Draining Lymph Node

Two subsets of murine splenic dendritic cells, derived from distinct precursors, can be distinguished by surface expression of CD8α homodimers. The functions of the two subsets remain controversial, although it has been suggested that the lymphoid-derived (CD8α(+)) subset induces tolerance, whereas...

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Detalles Bibliográficos
Autores principales: Smith, Adrian L., de St. Groth, Barbara Fazekas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192915/
https://www.ncbi.nlm.nih.gov/pubmed/9927521